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Search Results for " icg 001 "

4

Compounds

Cat No. Product Name Synonyms Targets
T6113 ICG-001 Apoptosis , Epigenetic Reader Domain , Wnt/beta-catenin
ICG-001 antagonizes Wnt/β-catenin/TCF-mediated transcription and specifically binds to element-binding protein (CBP) with IC50 of 3 μM, but is not the related transcriptional coactivator p300.
T2237 ICG001 Epigenetic Reader Domain , Wnt/beta-catenin
ICG001 (PRI-724 isomer) antagonizes Wnt/β-catenin/TCF-mediated transcription and specifically binds to element-binding protein (CREB)-binding protein (CBP) with IC50 of 3 μM, but is not the related transcriptional coacti...
T64414 PRI-724 C-82 prodrug,Foscenvivint Wnt/beta-catenin
PRI-724 (C-82 prodrug) is a selective small-molecule inhibitor of β-catenin/CBP interaction.
T65994 (6S)-N-Benzyl-6-(4-hydroxybenzyl)-8-(naphthalen-1-ylmethyl)-4,7-dioxohexahydro-2H-pyrazino[1,2-a]pyrimidine-1(6H)-carboxamide
Wnt signaling is required for direct multiple biological processes and also plays key roles in the pathogenesis of various diseases. Cyclic AMP response element-binding protein (CREB) is a transcription factor that is a ...
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